Simperic. 2, respectively, and for the Simparica Trio™ groups were 0 and 0. Simperic

 
2, respectively, and for the Simparica Trio™ groups were 0 and 0Simperic : G4321 (Act 36/1947)

The oral chew contains a specially optimised trio of ingredients for proven efficacy. 00 discount for agreeing to autoship. How to use simper in a sentence. 2 mg/kg sarolaner, 24 µg/kg moxidectin, and 5 mg/kg pyrantel (as pyrantel pamoate). 5 and 0, respectively. Side Effects: Short-term illness. Simparica should be administered at a dose of 2-4 mg/kg bodyweight in accordance with the following table: Use appropriate combination of available strengths to achieve the recommended dose of 2–4 mg/kg. Monthly Simparica Trio prevents heartworm disease, kills adult fleas and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations, and the treatment and control of roundworm and hookworm infections in dogs and puppies 8 weeks of age and older, and weighing 2. Simparica is a trusted oral medication for dogs that provides adequate monthly protection against fleas and ticks. Simparica Trio Chewable Tablets for Dogs works to prevent heartworms as well as treat lone star ticks, black-legged ticks, Gulf Coast ticks, American dog ticks, brown dog ticks, fleas, roundworms, and adult hookworms. 91 mg/lb) body weight. Simparica Trio has some essential qualities that make it so effective and popular among dog owners. 00 when you spend $100. 99, which is -12% off the average retail price of $161. 9%) voluntarily consumed by free choice without, or when offered in food. 5 kg. not these two things. It starts working fast* and goes strong for 35 days. 69. 0 mg/0. Simparica TRIO is a tasty monthly chew that provides triple protection against a trio of the biggest threats facing our dogs. A20: While Simparica Trio has been associated with adverse neurological reactions, including seizures, in rare cases, it is generally considered safe for use in dogs without a history of neurological issues. If your dog doesn't have those issues, you should be fine. No. If this occurs, notify your veterinarian. The safe use of Simparica TRIO has not been evaluated in breeding, pregnant, or lactating dogs. 3. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick “remedy”… and already several dogs have been adversely affected by this new drug. Simparica is a veterinary medicine used to treat infestations with ticks and fleas, demodectic and sarcoptic mange (skin infestations caused by two different types of mites) and ear mite infestations in dogs. Q. 0%. Moreover, Simparica Trio also prevents heartworm infection and protect against Lyme disease in dogs. com Simparica Trio is FDA-approved to block infections that may cause Lyme disease by killing deer ticks. Simparica Flea and Tick Chews for Small Dogs. QUALITATIVE AND QUANTITATIVE COMPOSITION. 048 mg/kg of moxidectin and 5–10 mg/kg of pyrantel in accordance with the following table: Bodyweight (kg) Tablet strength 3 mg/0. It has been demonstrated to be safe for puppies as young as 8 weeks old weighing 2. Each tablet is formulated to provide minimum dosages of 0. However, like any medication, it’s essential to use it correctly and monitor your pet for any potential side effects. 1 Simparica is FDA-approved to block infections that may cause Lyme. $20. Review product. Now, you can get year-tround protection against fleas and five kinds of ticks, total roundworm and hookworm control, and heartworm prevention with just one tasty, chewable dose a month. Simparica should be administered at a dose of 2-4 mg/kg bodyweight in accordance with the following table: Use appropriate combination of available strengths to achieve the recommended dose of 2–4 mg/kg. Simparica Trio® works to prevent heartworm disease, treat and prevent flea infestations, treat and control tick infestations, and treat and control roundworms and. 99. Prescription Item. Simparica Trio is a popular flea, tick, and worm preventative treatment for dogs. Prevention is. There are also “store brand” versions of these that you. simparica chewables is a fast acting oral flea and tick preventative tabs that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. Simparica Trio offers convenient, comprehensive protection against a range of common parasites. The regular use of these products is thought to give nearly 100% protection against ticks, although checking is still recommended. 1 to 44 pounds, 44. She also has the shakes from time to time. 2, respectively, and for the Simparica Trio™ groups were 0 and 0. Simparica Chewable Tablet for Dogs, 88. 6% reduction in adult fleas within 14 days after treatment and reached 100% on Day 60. Once ingested, Simparica works quickly to kill fleas (Ctenocephalides felis) on. 61 per dose. Simparica Trio, on the other hand, is a newer medication that contains three active. This product starts to eliminate fleas and ticks within few hours of administration. Simparica chewables are a well-tolerated, flea and tick protection for dogs that start working fast and remain effective for 5 weeks. Q. 8 pounds and older than 8 weeks of age. The treatment lasts for 35 days so monthly use is sufficient to keep your dog. In well-controlled laboratory studies, SIMPARICA demonstrated ≥Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica Trio Results Value: Simparica Trio Both preventatives are have six weight brackets to choose from: 2. K9 Advantix II Flea, Tick and Mosquito Prevention for Dogs, 6 Doses$91 now 16% off. 1-44 lbs is $95. Simparica Trio for dogs is an oral medication given monthly and used for the prevention of heartworm disease caused by Dirofilaria immitis. Nesse vídeo você vai aprender como usar o SIMPARIC, um comprimido mastigável palatável que elimina pulgas, carrapatos e sarna-----. Simparica Ingredients. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. Simparica Trio is particularly beneficial in regions with high prevalence of ticks, fleas, heartworm, and intestinal worms. Simparica Trio is a once-monthly chewable tablet that can treat existing flea and tick infestations and help prevent fleas, ticks, heartworm, roundworm and hookworm. The FDA has approved this product for use in dogs between 5. Nexgard Spectra. Simparica is the highly palatable new treatment for fleas, ticks and mites for dogs from eight weeks of age. diseases caused because of them. 1. FREE delivery on first-time orders. The medication is convenient to use and typically administered monthly. Nexgard uses Afoxoflaner and kills 100% of fleas in 24 hours. This class has been associated with neurologic adverse reactions. The average cost of Simparica ranges between $42 to $ 60 dollars for a 3 pack. Simparica kills adult fleas, and is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations from lonenstar ticks, Gulf Coast ticks, American dog tick, black-legged ticks and brown dog ticks for one month in dogs 6 months of age or older and weighing at least 2. 27 or 16. When fleas or ticks bite, they are exposed to. The cost of Simparica varies depending on the dosage strength and type. Simparica Trio Chewable Tablets for Dogs is a monthly oral medication that helps protect against fleas, ticks, heartworms, and other intestinal parasites in dogs. Which means you can be confident knowing between each. Coupon Codes 5. Então comprei um original para comparar. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. Simparica Trio 12mg Chewable Tablets for Dogs (5 - 10kg) are indicated for the treatment of dogs with, or at risk from, mixed external and internal parasitic infestations. Simparica Trio is a popular flea and tick preventative medication for dogs. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Simparica kills newly emerged fleas on the dog before they can lay eggs therefore preventing environmental flea contamination 1. Many traditional (and even some holistic) veterinarians are strongly recommending the use of the isoxazoline class of pSimparica Trio is a powerful, chewable medication designed to protect your four-legged friends from heartworm disease, ticks, fleas, and several internal parasites. burgdorferi infections as a direct result of killing I. After Simparica is given its activity against ticks and fleas lasts for at least 5 weeks. 8 pounds and 8 weeks old, but Heartgard Plus can be given to puppies as young as 6 weeks old. Administered as an easy once-a-month chewable tablet, Simparica provides continuous coverage for 35 days. Save 15% On Your Purchase with Simparica Flea And Tick Medication Coupon Code. Simparica Trio contains three active ingredients. Product Description. 8-5. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. Methods: Twenty-four laboratory Beagle dogs were implanted with 10 male and 10. 1-20 kg. It is indicated for the treatment and prevention of flea infestations. Simparica Trio can be given to puppies above 2. 99. Simparica has been administered orally to 8 week old Beagle puppies at doses of 0, 1, 3, and 5 times the maximum dose of 4 mg/kg at 28 day intervals for 10 doses. Simparica Trio starts working fast, and is approved to kill five types of ticks, while some competitive chewable brands are only approved to kill four. 54 mg/lb (1. 91 mg/lb (2 mg/kg). Tablets can be administered with or without food. Simparica 40mg Chewable Tablets are tasty chewable tablets used to treat tick, flea and sarcoptic mange infestations in dogs weighing >10kg - 20kg for up to 5 weeks. Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. Some limitations and restrictions may apply. 024–0. As per the vet, Simparica is an excellent flea and tick product that is available in oral form. This product is safe to use in dogs that are pregnant or breeding. Simparica Trio protects dogs from heartworms and other worms, plus fleas and ticks, all in one chewable pill. Simparica is a once-monthly, safe, and effective chewable flea and tick preventative for use in dogs. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica maybe be used as an alternative to the product NexGard. 01% of dogs taking this medication have experienced any neurologic side effects. Approved for use in dogs over the age of 8 weeks and above 2. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease, fleas & ticks, and roundworms & hookworms. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease, fleas & ticks, and roundworms & hookworms. Each tablet is formulated to provide minimum dosages of 1. Sarolaner inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular. Side Effects. 99. $ 65. . The mint box Simparica Chewable Tablets for Dogs, 22. com. Simparica 5 mg chewable tablets for dogs 1. It is exclusively indicated when use against ticks or fleas, and gastrointestinal nematodes are indicated at the same time. It’s the newer tablet-based Isoxazoline products that are the real game changers. com. 8 pounds. Simparica Trio kills fleas and paralysis ticks as well as provides persistent protection against flea and tick for five weeks. 1-44 lbs, (Mint Box), 6 Chewable Tablets (6-mos. 5–5 kg 10 for dogs >5–10 kg 20 for dogs >10–20 kg 40Simparica TRIO® Chewable Tablets for Dogs 12mg (5kg-10kg) SRP £0. Each tablet is formulated to provide minimum dosages of 0. $2898 ($4. Your credit card statement will reflect a charge by Vetsource for your purchase. This medicine protects your dog for 35 days, after which you can give your dog another dose. Pros: Fast acting, monthly administration, highly effective against fleas and ticks Cons: Does not prevent heartworm or treat intestinal parasites Simparica Trio:. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. This leads to uncontrollable neuromuscular. Available with a prescription only, this product works rapidly and offers a full month of protection. Simparica eliminates adult fleas within just three fours and ticks within just eight hours. 99. Sarolaner is an acaricide and insecticide belonging to the isoxazoline group. Simparica 10 mg chewable tablets for dogs >2. It kills ticks as well as fleas. It goes to work killing ticks within 8 hours and fleas within 3 hours, maintaining its. Simparica Trio tablets are palatable and readily consumed by the majority of dogs when offered by the owner. Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. Starting 9/1/2023, WalmartPetRx. Buy Simparica Chewable Tablet for Dogs, 44. Nexgard has Afoxolaner as its active ingredient while Simparica contains Sarolaner as its main ingredient. Compare Simparica vs. His metabolic panels were perfect and he is in great shape. 8 to 5. Simparica is highly palatable and is readily consumed by dogs when offered as treat, however tablets may also be given with a small amount of food or administered directly into the mouth; For dogs over 60 kg, administer an appropriate combination of chewable tablets to achieve the recommended dose rate of 2 to 4 mg/kg body weight. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease, fleas & ticks, and roundworms & hookworms. This class has been associated with neurologic adverse reactions including tremors, ataxia. 5–5 kg. Simparica Trio starts killing fleas within 4 hours and has a 100% effectiveness rate within 8 hours for the entire month. $51. Kills. Rating DistributionSIMPARICA ® (sarolaner) is a flavoured chewable tablet containing 5, 10, 20, 40, 80, or 120 mg of sarolaner, an ectoparasiticide intended for administration to dogs according to their weight. Simparica 88. Our Review of Simparica and Comfortis. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica Trio and Heartgard Plus are two powerful products in the pet market that holds a similarity in treating intestinal worms and preventing heartworms in dogs. 5 kg. Most dogs readily take this chewable tablet. Last updated November 21, 2023. Moxidectin, Pyrantel, and Saroloner are the three. 91 mg/lb) body weight. 91 mg/lb) body weight. 8 to 5. Simparica Trio is a chewable flavored tablet with a minimum label dosage of. This article provides comprehensive insights into the side effects of Simparica Trio, focusing on their duration and how to handle them. Jos koira ei vapaaehtoisesti syö tablettia, se voidaan antaa myös ruuan kanssatai suoraan suuhun. 2 mg/kg) sarolaner, 0. 78. 5, with an efficacy of 4. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Simparica Flea and Tick Chews for Tiny Dogs or Puppies. It is notably a medication for protection from Gulf coast. 11. Simparica Trio is a once-a-month, easy-to-give chewable that helps simplify protecting your pet every month. However, it cannot be used in pets under 6 months of age. Say goodbye to pesky, persistent pests and hello to Simparica. Simparica is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing lxodes scapularis vector ticks. Can dogs have a reaction to Simparica Trio? In a third field safety and effectiveness study, SIMPARICA TRIO was administered to 120 dogs with roundworms. If a dose is missed, administer SIMPARICA and resume a monthly dosing. The most frequently reported adverse. Simparica Trio is sarolaner, moxidectin, and pyrantel in a chewable once-a-month tablet with dosages based on the dog's size. The U. It is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations. Add to cart. It's a flavored, chewable tablet used by or on the order of a licensed veterinarian to: Prevent Borrelia burgdorferi infections caused by the killing of Ixodes scapularis vector ticks. Its action begins quickly and lasts for 30 days, making it an effective choice for busy pet owners. 00. Each package. Medicare. Nexgard does not last as long or provide the same powerful performance. Simparica uses Sarolaner which over stimulates the nervous system of the pests which kill fleas and ticks. 2-2. The Trio minimizes the risk of paralysis tick and tick infection by eliminating paralysis ticks and brown dog ticks. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease,. With three active ingredients designed for defense, Simparica Trio keeps dogs protected from heartworm disease, fleas & ticks, and roundworms & hookworms. It is much more effective than flea tick shampoos and spot ons in killing and clearing flea, tick, mite and lice infestation. This leads to uncontrollable neuromuscular. Then, it comes in chewable form in a tasty beef flavor. This also has been approved by FDA – Food, and Drug Administration department and is recommended by various vets as well. It can treat 5 parasites at a time and can protect well against heartworm disease, ticks & fleas, roundworms even hookworms. When comparing the prices of Nexgard and Simparica, they are close. 06 mg/12­. Gave my dog her monthly dose of Simparica (this is her 6th time taking it, no issues the other 5 months). at. Geometric mean worm counts for the placebo groups in Studies 1 and 2 were 21. Autoship. It is the first drug that combined three active ingredients - sarolaner, moxidectin, and pyrantel. Tabletteja ei saa jakaa. 25 kg. Food & Drink. Monthly Simparica Trio prevents heartworm disease, kills adult fleas and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations, and the treatment and control of roundworm and hookworm infections in dogs and puppies 8 weeks of age and older, and weighing 2. 00. Simparica has not been evaluated in pregnant, breeding or lactating dogs. com. Simparica is a flea tick chewable tablet from Zoetis USA whose primary ingredient is Sarolaner. Simparica Trio is an advanced liver-flavored chewable treatment designed specifically for dogs. Showing 12. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Approved for use in dogs over the age of 8 weeks and above 2. Safe for pregnant or nursing Pets. Simparica is a fast-acting liver flavored chewable tablet for flea and tick preventative that begins killing fleas and ticks within hours of administering and remains effective for one month to prevent re-infestations. 1x 10mg tablet for 5. Simparica TRIO (sarolaner, moxidectin, and pyrantel) is an oral medication for dogs that are at least 8 weeks old and weigh at least 2. †Toxocara canis, Toxascaris leonina, Ancylostoma caninum and Uncinaria. 5 mg. Shop all pharmacy flea & tick onlineSimparica Chewable tablet is a remarkable monthly flea and tick treatment for dogs and puppies. Simparica TRIO (6. Simparica Trio is a monthly chewable tablet for dogs that provides comprehensive protection against fleas, ticks, heartworms, and intestinal worms. Conclusion. 2. 8 to 5. Simparica was as effective as moxidectin/imidacloprid. 91 per dose. The Australian paralysis tick, Ixodes holocyclus, causes tick paralysis in dogs and cats in the eastern coastal regions of Australia. It is more expensive than using two different preventatives, but it is much more convenient. You can use Simparica Flea and Tick Medication monthly to keep your dogs safe. Simparica Trio should be stored at room temperature, in a dry place, out of direct sunlight. Subscribe & save on Simparica Trio® Chewables for. 91 mg/lb (2 mg/kg). Simparica is a safe, monthly chewable tick and flea preventative for dogs. supply) at Chewy. The range of Simparica includes Simparica Flea and Tick Chews and Simparica Trio Flea, Tick, Worm and Heartworm Chews. Simparica Trio (sarolaner / moxidectin / pyrantel) An overview of Simparica Trio and why it is authorised in the EU . Compare Simparica vs. Nexgard Spectra (afoxalaner and milbemycin) tablets for dogs (milbemycin is a dewormer) - lasts 1 month. Available by prescription, it works quickly and provides an entire month of protection. 91 mg/lb) body weight. 5, with an efficacy of 4. Neoterica Protecto 4 Flea and Tick Prevention for Dogs & Puppies - Flea Medicine & Home Pest Control - Topical Treatment & Mosquito Repellent for Dogs - Small, Medium and Extra Large Drops in Pack. 5 kg. Simparica can be offered by hand, in the food, or administered like other tablet medications. The material contained within this website is intended to be viewed by UK practising veterinary surgeons only. Nexgard is given every four weeks. Another possibility would be that the dosage was to high for her (simparica comes in three different dosages). Qual a dosagem de. See full Prescribing Information. When a parasite like a flea or tick bites your dog, they ingest the sarolaner along with their “meal,” which disrupts their nerve cell functions and kills them. Trifexis contains two active ingredients - Spinosad and Milbemycin Oxime. Each tablet is formulated to provide a minimum sarolaner dosage of 2 mg/kg (0. Nexgard starts killing fleas in 4 hours and ticks in 48 hours. Purchased in Sept 2021 for $53. Simparica is given orally once a month at the recommended minimum dosage of 0. In one study, nine of the tenDe ação rápida, Simparic faz efeito em 3 horas e se mantém por até 35 dias. Simparica for dogs is a medication designed to prevent this. Simparica provides immediate and persistent flea killing activity up to and beyond the monthly treatment interval, minimising the risk of protection gaps. Tel: 0345 300 8034. 61 per dose. 1-22 lbs. It is the first drug that combined three active ingredients - sarolaner, moxidectin, and pyrantel. Simerics-MP CFD for Autodesk® Fusion 360®. Simparica® Chewable Tablets for Dogs 20mg (5kg-10kg) SRP £36. Simparica Trio™ was well-tolerated and a diverse range of concomitant medications were administered to dogs during the course of the study. Bravecto kills many types of ticks including the lone star tick for 8 weeks. Check now for Today's best Simparica Promo Code: Get 10% Off With Simparica Promo Code - Limited Time Offer! BLACK FRIDAY DAY 2023 is Comming: 100K+ Coupons & Deals Up to 85%! Category . Description. As pet parents, we strive to ensure our furry companions stay healthy and protected from harmful parasites. It contains sarolaner, which kills fleas and ticks, moxidectin, which helps prevent heartworm disease and pyrantel, which treats and controls roundworm and hookworm. ; It can eliminate as many as five tick species: gulf coast. Simparica Trio from Zoetis Petcare provides flea, tick and heartworm prevention for dogs, plus targeted intestinal parasite control that lasts for an entire month. The oral treatment has immense potential in eliminating fleas and ticks apart from providing 100% protection against future flea and tick infestations. Simparica is a tasty chewable flea treatment that goes down a treat protecting your dog against fleas, ticks, mites and sarcoptic mange from 8 weeks of age. Simparica Trio is the first and only product that combines sarolaner, moxidectin and pyrantel in each treatment to help prevent heartworm disease, kill fleas before they can lay eggs, kill 5 types of ticks, treat and prevent flea infestations and treat and control roundworms and hookworms. Off-label, it is used to manage ear mite infestations, sarcoptic and demodectic mange. 5 kg 5 for dogs >2. Simparica 20 mg chewable tablets for dogs >5–10 kg. It’s available with a veterinarian prescription and is backed by a 100%. It is also used off-label. How Simparica® & Simparica Trio® Works Concurrently, the agency has also approved Bravecto, Nexgard, Simparica and Credelio after careful review of the studies and the additional data related to safety; and declared the products continue to be safe for most animals. 8 pounds. 8 pounds or more, tab Simparica kills adult fleas and is recommended for the treatment and control of tick infestations caused by Amblyomma maculatum, Dermacentor variabilis, Ixodes scapularis, and. 48 or $15. 4 mg/kg of sarolaner, 0. How long does Simparica protection last? Simparica is a monthly chewable whose 35-day protection period begins in hours. • 2 yr. Once administered, Simparica chewable for dogs starts killing fleas within 3 hours of. Simparica Trio® is intended for. 67 or $16. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Compared with the other isoxazoline tablets ( NEXGARD with afoxolaner , BRAVECTO with fluralaner ), SIMPARICA controls not only ticks and fleas, but also mange mites ( Sarcoptes scabiei) after two consecutive monthly treatments. By killing ticks, it prevents diseases in. It starts working fast* and goes strong for 35 days. Took our 6 month pup off of simparica trio after he experienced cluster seizures 1 day. Simparica Trio is the first and only product that combines sarolaner, moxidectin, and pyrantel in one simple-to-give chewable—for protection against: *Amblyomma americanum, Amblyomma maculatum, Dermacentor variabilis, Ixodes scapularis, Rhipicephalus sanguineus. 1-132 lbs. Simparica is an oral medication that is used to prevent and treat flea and tick infestations in dogs. Simparica and Bravecto Active Ingredients Comparison. Heartgard, on the other hand, is a veteran in the field, predominantly known for its effectiveness against. 99 Chewy Price. It is the most convenient flea and tick protection product on the market. Starting 12/31/2023, WalmartPetRx. Sarolaner restricts the function of the nerves at the neuromuscular junction in parasites. Simparica starts killing fleas within 3 hours and ticks within 8 hours and keeps going strong for 35 days without losing effectiveness at the end of the month. The dosage depends on the dog weight and age. Simparica Trio is the first FDA-approved monthly chewable that protects your dog against heartworm disease, ticks, fleas, roundworms, and hookworms. He had been taking the it for about 2-3 months. They are both chewable, once-monthly, prescription-only tablets. Simparica (sarolaner) Chewables are safe, monthly flea and tick protection for dogs that start working fast and remain effective all month long. Simparica Trio is a once-a-month, easy-to-give chewable that helps simplify protecting your pet every month. Sarolaner is also used in combination products for both dogs and cats. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is. Sarolaner inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor, and works at the. Sarolaner is an acaricide and insecticide belonging to the isoxazoline group. 1 to 132 pounds, along with three options for the number of chewables to purchase at one time: three, six, or twelve. FREE shipping and the BEST customer service! Simparica is the only monthly tick and flea chewable for dogs approved to kill 5 types of ticks: Gulf Coast tick, Brown dog tick, Deer tick/black-legged tick, American dog tick, Lone Star tick. Simparica prevents and treats infestations with fleas and ticks. Simparica Flea and Tick Control Chewable Tablets are indicated for the treatment of tick and flea infestations, with an immediate and persistent killing activity for at least 5 weeks. Tablet strength 6 mg/0. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. 1 to 44 pounds, 44. It breaks flea life cycle and controls flea allergy dermatitis. 91 per dose. 2 mg/kg sarolaner, 24 µg/kg moxidectin, and 5 mg/kg pyrantel (as pyrantel pamoate).